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Central America & Mexico Cruises

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Explore these 22 top Central America & Mexico cruises for 2024 and 2025. Some of the most popular activities on our Central America & Mexico trips include cruises, wildlife viewing, small ship cruises, snorkeling, and kayaking. Discover Panama Canal, Quepos, Colon, Loreto, and Puerto Caldera with your expert local English-speaking guides who will show you the hot spots and the off-the-beaten-path hidden gems. We work with only the best small ships that carry under 500 fortunate guests, and we can give you unbiased advice to match you with the perfect ship and perfect cruise for your next vacation. Our Central America & Mexico cruises start from $1,640 for cruises of 6 to 15 days. Contact one of Adventure Life's Central America & Mexico cruise specialists for help planning a seamless trip.
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    • Central America & Mexico
Crossing a stream on Osa Peninsula
$11,295
EXPLORE

Costa Rica & Panama Canal

Costa Rica - Colombia - 12 Day Itinerary aboard Greg Mortimer
  • Explore Costa Rica's wildlife
  • Discover vibrant bird species
  • Learn about the Emberá tribe
  • Cross the Panama Canal
  • Visit Curú National Wildlife Refuge
Starts / Ends:
San Jose / Colon
Activities:
Archaeological Site Visits, Photography Seminars, Scuba Diving, Small Ship Cruises, Snorkeling, Stand Up Paddle Boarding, Village Visits, Whale Watching, Wildlife Viewing
Activity Level:
Variable
Immerse in the coastal landscapes of Costa Rica and Panama on this 12-day cruise aboard Greg Mortimer with travel photographerRichard I'Anson. Costa Rica stands as one of the world's most biodiverse regions, offering opportunities to explore lush tropical rainforests with a remarkable array …
Cruise Details
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Panama adventure
$1,840
Savings
EXPLORE

Panama to Costa Rica

8 Day Itinerary aboard Star Clipper
  • Visit the Caribbean world
  • Swim & snorkel at the Pearl Islands
  • Enjoy Isla Tortuga’s beaches
  • Discover diverse tropical ecosystem
Starts / Ends:
Balboa / Puntarenas
Activities:
Rainforest Exploration, Small Ship Sailing, Snorkeling
Activity Level:
Variable
This 8-day Central America adventure cruise departs from Balboa, Panama, to Puntarenas, Costa Rica. The waters of San Jose Island are considered to be among the best deep-sea fishing grounds in the world due to their abundance of tropical game species. Then, spend a few days at sea exploring …
Cruise Details
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Explore beautiful Costa Rica
$1,640
Savings
EXPLORE

Costa Rica & Panama

Puerto Caldera Roundtrip - 8 Day Itinerary aboard Star Clipper
  • Enjoy Isla Tortugas
  • Discover diverse tropical ecosystem
  • Explore Coiba National Park
  • Visit Golfo de Chiriquí
Starts / Ends:
Puerto Caldera / Puerto Caldera
Activities:
Horseback Riding, Kayaking, Small Ship Cruises, Wildlife Viewing
Activity Level:
Variable
This 8-day Central America adventure cruise departs from Puerto Caldera. The waters of San Jose Island are considered to be among the best deep-sea fishing grounds in the world due to their abundance of tropical game species. Then, spend a few days at sea exploring islands and participating in Star …
Cruise Details
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Costa Rica Toucan Bird
$1,640
Savings
EXPLORE

Costa Rica to Panama

8 Day Itinerary aboard Star Clipper
  • Visit Golfo de Chiriquí
  • Swim & snorkel at the Pearl Islands
  • Enjoy Isla Tortuga’s beaches
  • Discover diverse tropical ecosystem
Starts / Ends:
Puerto Caldera / Balboa
Activities:
Rainforest Exploration, Small Ship Sailing, Snorkeling
Activity Level:
Variable
Join Star Clipper on this 8-day cruise from Puerto Caldera, Costa Rica, to Balboa, Panama. Set sail through the Tortugas, regarded as the most beautiful island in Costa Rica. Then visit the small, busy town of Quepos, which serves as the gateway to the Manuel Antonio National Park. Discover Golfo …
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Isla Tortuga
$1,640
Savings
EXPLORE

Costa Rica & Nicaragua

Puerto Caldera Roundtrip - 8 Day Itinerary aboard Star Clipper
  • Explore Manuel Antonio Park
  • Experience San Juan del Sur
  • Relax on Playa Nacascolo
  • Enjoy Isla Tortuga
Starts / Ends:
Puerto Caldera / Puerto Caldera
Activities:
Small Ship Sailing
Activity Level:
Variable
Embark on an 8-day cruise aboard the Star Clipper, starting in Puerto Caldera, Costa Rica, the gateway to the Pacific Coast. Explore the impressive Arenal Volcano and witness its natural beauty. Next, head to Quepos, a small town with an authentic feel, serving as the entrance to Manuel Antonio …
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San Blas
$7,090
EXPLORE

Secrets of Central America

Colon - Puntarenas - 11 Day Itinerary aboard Le Bellot
  • Explore Fort San Lorenzo
  • Discover San Blas Islands
  • Experience Panama Canal
  • Swim in the Pearl Islands
Starts / Ends:
Colon / Puntarenas
Activities:
Small Ship Cruises, Wildlife Viewing
Activity Level:
Variable
Embark on an 11-day expedition cruise from Colon to Puntarenas aboard the Le Bellot. Visit San Lorenzo’s Fort, an extraordinary fortress safeguarding transatlantic trade. Next, explore the San Blas Islands, home to the Kuna people and their vibrant craft of molas. Cross the legendary Panama …
Cruise Details
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Keel-billed Toucan
$6,054
EXPLORE

Panama and Costa Rica by Sea: The Natural Wonders of Central America – with Smithsonian Journeys

8 Day Itinerary aboard Le Bellot
  • Cross the Panama Canal
  • Punta Culebra Nature Center at STRI
  • Snorkel on beautiful Holandes Cayes
  • See Darién National Park rainforest
Starts / Ends:
Colon / Puerto Caldera
Activities:
Rainforest Exploration, Small Ship Cruises, Snorkeling, Wildlife Viewing
Activity Level:
Variable
The San Blas Islands of Holandes Cayes, Panama City's Old Quarter, and the Darién National Park are highlights of Le Bellot's journey in Central America. Proceed to Fuente Amador and start your exploration of the Panama Canal. In Costa Rica, you may encounter sloths, the noisy howler …
Cruise Details
0
$6,500
GroupSave
EXPLORE

Northern Gulf of California: Whales, Birds & Sealife Adventure

San Jose del Cabo Roundtrip - 11 Day Itinerary aboard Safari Voyager
  • Visit Sea of Cortes UNESCO
  • Diverse Birdwatching
  • Seasonal Wildlife Spectacles
  • Snorkel with Sea Lions & reef fish
Starts / Ends:
San Jose del Cabo / San Jose del Cabo
Activities:
Hiking, Kayaking, Snorkeling, Whale Watching, Wildlife Viewing
Activity Level:
Relaxed
Delve into an 11-day cruise in the northern Baja Peninsula aboard Safari Voyager.Explore the UNESCO World Heritage Site of the Sea of Cortes, a marine life-rich natural aquarium. Snorkel alongside sea lion pups and vibrant reef fish, embark on mule rides with local rancheros, and marvel at the …
Cruise Details
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Trekking through Corcovado National Park in Costa Rica.
$6,601
EXPLORE

Costa Rica & the Panama Canal

8 Day Itinerary aboard National Geographic Quest
  • Observe animals in their habitat
  • Kayak through magical mangroves
  • Transit the historical Panama Canal
  • Explore Gulf of Panama beaches
Activities:
Horseback Riding, Kayaking, Small Ship Cruises, Snorkeling, Stand Up Paddle Boarding, Wildlife Viewing
Activity Level:
Relaxed
Join the National Geographic Quest onthis 8-dayexpedition to Costa Rica and the Panama Canal.Discover diverse wilderness and jungle wildlife coupled with an in-depth crossing of the Panama Canal, a marvel of engineering, and gain special access to the Smithsonian Tropical Research Institute in the …
Cruise Details
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Dolphins race through the water in Baja.
$12,726
EXPLORE

Baja California: A Remarkable Journey

15 Day Itinerary aboard National Geographic Venture
  • See gray, sperm, blue & fin whales
  • Hike islands of Gulf of California
  • Snorkel among playful sea lions
  • Learn photo techniques from experts
Starts / Ends:
Loreto / Loreto
Activities:
Kayaking, Photography Seminars, Small Ship Cruises, Snorkeling, Whale Watching, Wildlife Viewing
Activity Level:
Variable
Your 15-day remarkable cruise offers the most comprehensive Baja California and the Sea of Cortez experience available. This is a true expedition, which means that your captain plans day-by-day movements and itinerary according to the conditions that best offer sightings and up-close encounters …
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Cabo Pulmo
$7,000
EXPLORE

Baja California: Among the Great Whales

8 Day Itinerary aboard National Geographic Venture
  • Observe California gray whales
  • Hike across desert islands
  • Experience the Baja California
  • Snorkel with sea lions
Starts / Ends:
Puerto San Carlos / Loreto
Activities:
Hiking, Small Ship Cruises, Snorkeling, Whale Watching, Wildlife Viewing
Activity Level:
Variable
Experience Baja in full with visits to lively La Paz and lovely Loreto. La Paz invites you to follow your curiosity into a maze of quaint streets and sun-drenched promenades, promising discoveries of all kinds. Loreto, a charming coastal town spectacularly backed by the Sierra de la Giganta …
Cruise Details
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Panama City's Bridge of the Americas
$11,675
EXPLORE

Once through the Panama Canal

Panama to Costa RIca - 11 Day Itinerary aboard Sea Cloud Spirit
  • Cruise through the Panama Canal
  • Encounter islands & national parks
  • Discover Palo Verde National Park
  • Spot Coatis, jaguars and birds
Starts / Ends:
Colon / Puntarenas
Activities:
Wildlife Viewing
Activity Level:
Relaxed
Embark on an 11-day cruise through the historic Panama Canal, start in Panama City and. experience a dinner cruise through the iconic Panama canal, exploring Gatúnsee's unique islands like Barro Colorado in the rainforest. Sail through the canal's 12 lock basins, showcasing its …
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Spot stunning wildlife in the tree canopy
$4,190
EXPLORE

Wild Costa Rica Escape

6 Day Itinerary aboard National Geographic Quest
  • Navigate Costa Rica’s Guanacaste
  • Discover diverse tropical ecosystem
  • Enjoy Isla Tortuga’s beaches
  • Explore volcanic landscapes
Starts / Ends:
Puerto Caldera / Puerto Caldera
Activities:
Horseback Riding, Kayaking, Small Ship Cruises, Snorkeling, Wildlife Viewing
Activity Level:
Relaxed
Discover the treasures of Guanacaste, one of Costa Rica’s richest regions, on a six-day voyage aboard National Geographic Quest. Snorkel and kayak among untouched corals and palm-lined beaches in the Guanacaste Conservation Area, a UNESCO World Heritage site. Hike, ride horseback, and zipline …
Cruise Details
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Look for unique birds and other wildlife in the rain forest!
$11,675
EXPLORE

Natural Wonders, Engineering Marvels

Puntarenas - Panama City - 11 Day Itinerary aboard Sea Cloud Spirit
  • Explore Nicoya Peninsula beaches
  • Discover Pearl Islands Discover Pea
  • Visit Manuel Antonio Park's
  • Sail through the Panama Canal
Starts / Ends:
Puntarenas / Colon
Activities:
Rainforest Exploration
Activity Level:
Relaxed
Embark on an 11-day cruise from Puntarenas to Panama City, unveiling "Pura Vida" spirit. Explore Puntarenas' cultural tapestry, venture to Puerto Jiménez's pristine jungles, and discover Marina Flamingo's luxury. Sail the Pacific, unwind at Playa Panama, and navigate …
Cruise Details
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Zapatilla Cay, Panama
$6,290
EXPLORE

Panama and Colombia: Exploring the Caribbean Coast

8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Meet Indigenous people of Guna Yala
  • Look for unique tropical wildlife
  • See colonial architecture
Starts / Ends:
Panama City / Cartagena
Activities:
Small Ship Cruises, Wildlife Viewing
Activity Level:
Relaxed
Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coast of Panama and Colombia on this 8-day cruise aboard theNational Geographic Quest. Hike into dense rainforests that harbor extraordinary biodiversity, glide through little-explored inlets by Zodiac and …
Cruise Details
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Scenic Landscape
$3,677
EXPLORE

Wild Baja Escape: The Whales of Magdalena Bay

6 Day Itinerary aboard National Geographic Sea Bird
  • Discover whales in Magdalena Bay
  • Hike through island landscapes
  • Kayak on the glassy waters
  • Learn about ecosystems
Starts / Ends:
Loreto / Puerto San Carlos
Activities:
Kayaking, Small Ship Cruises, Whale Watching, Wildlife Viewing
Activity Level:
Variable
Spend six days with majestic gray whales and their curious calves in Mexico's Bahia Almejas, one of the best locations in the world to observe gray whale mother-calf interactions. From the luxury of National Geographic Sea Bird, take in the sights and sounds of the bay before embarking on an …
Cruise Details
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Scenic Landscape
$3,677
EXPLORE

Wild Baja Escape: The Whales of Magdalena Bay

6 Day Itinerary aboard National Geographic Sea Lion
  • Discover whales in Magdalena Bay
  • Hike through island landscapes
  • Kayak on the glassy waters
  • Learn about ecosystems
Starts / Ends:
Loreto / Puerto San Carlos
Activities:
Kayaking, Small Ship Cruises, Whale Watching, Wildlife Viewing
Activity Level:
Variable
Spend six days with majestic gray whales and their curious calves in Mexico's Bahia Magdalena, one of the best locations in the world to observe gray whale mother-calf interactions. From the luxury of National Geographic Sea Lion, take in the sights and sounds of the bay before embarking on an …
Cruise Details
0
Boats Moored to the Quay at Bridgetown Harbour
$4,440
Savings
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Royal Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends:
Bridgetown / Balboa
Activities:
Small Ship Cruises, Small Ship Sailing, Snorkeling, Wildlife Viewing
Activity Level:
Variable
Royal Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
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